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Characterization and immunological aspects of Borrelia burgdorferi pleomorphic round bodies
Meriläinen, Leena (University of Jyväskylä, 2015) -
Borrelia burgdorferi Outer Membrane Vesicles Contain Antigenic Proteins, but Do Not Induce Cell Death in Human Cells
Karvonen, Kati; Tammisto, Hanna; Nykky, Jonna; Gilbert, Leona (MDPI AG, 2022)Like many bacterial species, Borrelia burgdorferi, the pleomorphic bacterium that causes Lyme borreliosis, produces outer membrane vesicles (OMVs). Borrelial OMVs (BbOMVs) have been identified as containing virulence ... -
Rodent host population dynamics drive zoonotic Lyme Borreliosis and Orthohantavirus infections in humans in Northern Europe
Aminikhah, Mahdi; Forsman, Jukka T.; Koskela, Esa; Mappes, Tapio; Sane, Jussi; Ollgren, Jukka; Kivelä, Sami M.; Kallio, Eva R. (Nature Publishing Group, 2021)Zoonotic diseases, caused by pathogens transmitted between other vertebrate animals and humans, pose a major risk to human health. Rodents are important reservoir hosts for many zoonotic pathogens, and rodent population ... -
Predicting habitat suitability for Ixodes ricinus and Ixodes persulcatus ticks in Finland
Uusitalo, Ruut; Siljander, Mika; Lindén, Andreas; Sormunen, Jani J.; Aalto, Juha; Hendrickx, Guy; Kallio, Eva; Vajda, Andrea; Gregow, Hilppa; Henttonen, Heikki; Marsboom, Cedric; Korhonen, Essi M.; Sironen, Tarja; Pellikka, Petri; Vapalahti, Olli (Biomed Central, 2022)Background Ticks are responsible for transmitting several notable pathogens worldwide. Finland lies in a zone where two human-biting tick species co-occur: Ixodes ricinus and Ixodes persulcatus. Tick densities have increased ... -
Effects of rodent abundance on ticks and Borrelia: results from an experimental and observational study in an island system
Kiran, Nosheen; Brila, Ilze; Mappes, Tapio; Sipari, Saana; Wang, Yingying; Welsh, Erin; Kallio, Eva R. (BioMed Central, 2024)Background Lyme borreliosis is the most common tick-borne disease in Europe and is often caused by Borrelia afzelii, which is transmitted by Ixodes ricinus ticks. The prevalence and abundance of infected ticks fluctuate ...