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dc.contributor.authorZhang, Jingyu
dc.contributor.authorXia, Wei
dc.contributor.authorHuda, Saskia
dc.contributor.authorWard, Jas S.
dc.contributor.authorRissanen, Kari
dc.contributor.authorAlbrecht, Markus
dc.date.accessioned2021-05-26T05:28:36Z
dc.date.available2021-05-26T05:28:36Z
dc.date.issued2021
dc.identifier.citationZhang, J., Xia, W., Huda, S., Ward, J. S., Rissanen, K., & Albrecht, M. (2021). Synthesis of N‐Fused Indolines via Copper (II)‐Catalyzed Dearomatizing Cyclization of Indoles. <i>Advanced Synthesis and Catalysis</i>, <i>363</i>(12), 3121-3126. <a href="https://doi.org/10.1002/adsc.202100290" target="_blank">https://doi.org/10.1002/adsc.202100290</a>
dc.identifier.otherCONVID_89705069
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/75948
dc.description.abstractHerein, a copper(II)-catalyzed dearomative cyclization amination of N-(2-aminobenzoyl) indoles is presented. Under mild reaction conditions, the cyclization proceeds to afford tetracyclic indolines by forming a new C−N bond in good yields. The tetracyclic 5a,6-dihydroindolo[2,1-b]quinazolin-12(5H)-ones are obtained in good to excellent yields (up to 99% yield) by using trifluoromethanesulfonic acid (TfOH) mediated N−Ts bond cleavage. The obtained compounds could be easily functionalized by simple synthetic methods.en
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofseriesAdvanced Synthesis and Catalysis
dc.rightsCC BY-NC-ND 4.0
dc.titleSynthesis of N‐Fused Indolines via Copper (II)‐Catalyzed Dearomatizing Cyclization of Indoles
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202105263205
dc.contributor.laitosKemian laitosfi
dc.contributor.laitosDepartment of Chemistryen
dc.contributor.oppiaineOrgaaninen kemiafi
dc.contributor.oppiaineOrganic Chemistryen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.format.pagerange3121-3126
dc.relation.issn1615-4150
dc.relation.numberinseries12
dc.relation.volume363
dc.type.versionpublishedVersion
dc.rights.copyright© 2021 The Authors. Advanced Synthesis & Catalysis published by Wiley-VCH GmbH.
dc.rights.accesslevelopenAccessfi
dc.subject.ysoaromaattiset yhdisteet
dc.subject.ysoorgaaniset yhdisteet
dc.subject.ysokupari
dc.subject.ysokatalyysi
dc.subject.ysokemiallinen synteesi
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p23502
jyx.subject.urihttp://www.yso.fi/onto/yso/p3841
jyx.subject.urihttp://www.yso.fi/onto/yso/p19074
jyx.subject.urihttp://www.yso.fi/onto/yso/p8704
jyx.subject.urihttp://www.yso.fi/onto/yso/p8468
dc.rights.urlhttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.relation.doi10.1002/adsc.202100290
jyx.fundinginformationJingyu Zhang gratefully acknowledges support by the Chinese Scholarship Council (CSC), Jas S. Ward the Finnish Cultural Foundation Central Fund (grant number 00201148) and Kari Rissanen the Alexander von Humboldt Foundation. (AvH research award) Open access funding enabled and organized by Projekt DEAL.
dc.type.okmA1


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