Näytä suppeat kuvailutiedot

dc.contributor.authorXu, Qianru
dc.contributor.authorYe, Chaoxiong
dc.contributor.authorHämäläinen, Jarmo A.
dc.contributor.authorRuohonen, Elisa M.
dc.contributor.authorLi, Xueqiao
dc.contributor.authorAstikainen, Piia
dc.date.accessioned2021-04-16T11:06:36Z
dc.date.available2021-04-16T11:06:36Z
dc.date.issued2021
dc.identifier.citationXu, Q., Ye, C., Hämäläinen, J. A., Ruohonen, E. M., Li, X., & Astikainen, P. (2021). Magnetoencephalography Responses to Unpredictable and Predictable Rare Somatosensory Stimuli in Healthy Adult Humans. <i>Frontiers in Human Neuroscience</i>, <i>15</i>, Article 641273. <a href="https://doi.org/10.3389/fnhum.2021.641273" target="_blank">https://doi.org/10.3389/fnhum.2021.641273</a>
dc.identifier.otherCONVID_66419960
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/75092
dc.description.abstractMismatch brain responses to unpredicted rare stimuli are suggested to be a neural indicator of prediction error, but this has rarely been studied in the somatosensory modality. Here, we investigated how the brain responds to unpredictable and predictable rare events. Magnetoencephalography responses were measured in adults frequently presented with somatosensory stimuli (FRE) that were occasionally replaced by two consecutively presented rare stimuli [unpredictable rare stimulus (UR) and predictable rare stimulus (PR); p = 0.1 for each]. The FRE and PR were electrical stimulations administered to either the little finger or the forefinger in a counterbalanced manner between the two conditions. The UR was a simultaneous electrical stimulation to both the forefinger and the little finger (for a smaller subgroup, the UR and FRE were counterbalanced for the stimulus properties). The grand-averaged responses were characterized by two main components: one at 30–100 ms (M55) and the other at 130–230 ms (M150) latency. Source-level analysis was conducted for the primary somatosensory cortex (SI) and the secondary somatosensory cortex (SII). The M55 responses were larger for the UR and PR than for the FRE in both the SI and the SII areas and were larger for the UR than for the PR. For M150, both investigated areas showed increased activity for the UR and the PR compared to the FRE. Interestingly, although the UR was larger in stimulus energy (stimulation of two fingers at the same time) and had a larger prediction error potential than the PR, the M150 responses to these two rare stimuli did not differ in source strength in either the SI or the SII area. The results suggest that M55, but not M150, can possibly be associated with prediction error signals. These findings highlight the need for disentangling prediction error and rareness-related effects in future studies investigating prediction error signals.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherFrontiers Media SA
dc.relation.ispartofseriesFrontiers in Human Neuroscience
dc.rightsCC BY 4.0
dc.subject.otherdeviance detection
dc.subject.othermagnetoencephalography
dc.subject.otherpredictability
dc.subject.otherprediction error
dc.subject.othersomatosensory
dc.titleMagnetoencephalography Responses to Unpredictable and Predictable Rare Somatosensory Stimuli in Healthy Adult Humans
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202104162397
dc.contributor.laitosPsykologian laitosfi
dc.contributor.laitosDepartment of Psychologyen
dc.contributor.oppiainePsykologiafi
dc.contributor.oppiaineMonitieteinen aivotutkimuskeskusfi
dc.contributor.oppiaineHyvinvoinnin tutkimuksen yhteisöfi
dc.contributor.oppiainePsychologyen
dc.contributor.oppiaineCentre for Interdisciplinary Brain Researchen
dc.contributor.oppiaineSchool of Wellbeingen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.description.reviewstatuspeerReviewed
dc.relation.issn1662-5161
dc.relation.volume15
dc.type.versionacceptedVersion
dc.rights.copyright© 2021 Xu, Ye, Hämäläinen, Ruohonen, Li and Astikainen
dc.rights.accesslevelopenAccessfi
dc.relation.grantnumber333649
dc.subject.ysoMEG
dc.subject.ysoennustettavuus
dc.subject.ysoärsykkeet
dc.subject.ysotuntoaisti
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p3329
jyx.subject.urihttp://www.yso.fi/onto/yso/p9701
jyx.subject.urihttp://www.yso.fi/onto/yso/p2943
jyx.subject.urihttp://www.yso.fi/onto/yso/p3330
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.3389/fnhum.2021.641273
dc.relation.funderResearch Council of Finlanden
dc.relation.funderSuomen Akatemiafi
jyx.fundingprogramPostdoctoral Researcher, AoFen
jyx.fundingprogramTutkijatohtori, SAfi
jyx.fundinginformationThis work was supported by grants from the National Natural Science Foundation of China (No. 31700948 to CY) and the Academy of Finland (No. 333649 to CY). The National Natural Science Foundation of China provided funding for the open-access publication fee.
dc.type.okmA1


Aineistoon kuuluvat tiedostot

Thumbnail

Aineisto kuuluu seuraaviin kokoelmiin

Näytä suppeat kuvailutiedot

CC BY 4.0
Ellei muuten mainita, aineiston lisenssi on CC BY 4.0