Show simple item record

dc.contributor.authorIsiozor, Nzechukwu M.
dc.contributor.authorKunutsor, Setor K.
dc.contributor.authorVoutilainen, Ari
dc.contributor.authorKurl, Sudhir
dc.contributor.authorKauhanen, Jussi
dc.contributor.authorLaukkanen, Jari A.
dc.date.accessioned2021-03-10T09:33:23Z
dc.date.available2021-03-10T09:33:23Z
dc.date.issued2021
dc.identifier.citationIsiozor, N. M., Kunutsor, S. K., Voutilainen, A., Kurl, S., Kauhanen, J., & Laukkanen, J. A. (2021). Association between ideal cardiovascular health and risk of sudden cardiac death and all-cause mortality among middle-aged men in Finland. <i>European Journal of Preventive Cardiology</i>, <i>28</i>(3), 294-300. <a href="https://doi.org/10.1177/2047487320915338" target="_blank">https://doi.org/10.1177/2047487320915338</a>
dc.identifier.otherCONVID_35160028
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/74578
dc.description.abstractBackground Strong associations have been demonstrated between the American Heart Association’s cardiovascular health (CVH) metrics and various cardiovascular outcomes, but the association with sudden cardiac death (SCD) is uncertain. We examined the associations between these CVH metrics and the risks of SCD and all-cause mortality among men in Finland. Methods and results We used the prospective population-based Kuopio Ischaemic Heart Disease cohort study, which consists of men between 42 and 60 years of age at baseline. CVH metrics were computed for 2577 men with CVH scores at baseline ranging from 0 to 7, categorized into CVH scores of 0–2 (poor), 3–4 (intermediate) and 5–7 (ideal). Multivariate Cox regression models were used to estimate the hazards ratios (HRs) and 95% confidence intervals (CIs) of ideal CVH metrics for SCD and all-cause mortality. During a median follow-up period of 25.8 years, 280 SCDs and 1289 all-cause mortality events were recorded. The risks of SCD and all-cause mortality decreased continuously with increasing number of CVH metrics across the range 2–7 (p value for non-linearity for all <0.05). In multivariable analyses, men with an ideal CVH score had an 85% reduced risk of SCD compared with men with a poor CVH score (HR 0.15; 95% CI 0.05–0.48; p = 0.001). For all-cause mortality, there was a 67% lower risk among men with an ideal CVH score compared with those with a poor CVH score (HR 0.33; 95% CI 0.23–0.49; p <0.001). Conclusions Ideal CVH metrics were strongly and linearly associated with decreased risks of SCD and all-cause mortality among middle-aged men in Finland.en
dc.format.mimetypeapplication/pdf
dc.languageeng
dc.language.isoeng
dc.publisherSage Publications
dc.relation.ispartofseriesEuropean Journal of Preventive Cardiology
dc.rightsCC BY 4.0
dc.subject.othercardiovascular health metrics
dc.subject.othersudden cardiac death
dc.subject.otherall-cause mortality
dc.subject.otherrisk factors
dc.subject.othermen
dc.titleAssociation between ideal cardiovascular health and risk of sudden cardiac death and all-cause mortality among middle-aged men in Finland
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-202103101929
dc.contributor.laitosLiikuntatieteellinen tiedekuntafi
dc.contributor.laitosFaculty of Sport and Health Sciencesen
dc.contributor.oppiaineLiikuntalääketiedefi
dc.contributor.oppiaineSports and Exercise Medicineen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.description.reviewstatuspeerReviewed
dc.format.pagerange294-300
dc.relation.issn2047-4873
dc.relation.numberinseries3
dc.relation.volume28
dc.type.versionpublishedVersion
dc.rights.copyright© The European Society of Cardiology 2020
dc.rights.accesslevelopenAccessfi
dc.subject.ysosydän- ja verisuonitaudit
dc.subject.ysoriskitekijät
dc.subject.ysokuolleisuus
dc.subject.ysomiehet
dc.subject.ysofyysinen kunto
dc.subject.ysoäkkikuolema
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p9886
jyx.subject.urihttp://www.yso.fi/onto/yso/p13277
jyx.subject.urihttp://www.yso.fi/onto/yso/p5003
jyx.subject.urihttp://www.yso.fi/onto/yso/p8173
jyx.subject.urihttp://www.yso.fi/onto/yso/p7384
jyx.subject.urihttp://www.yso.fi/onto/yso/p7352
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.1177/2047487320915338
jyx.fundinginformationProf. Laukkanen acknowledges support from The Finnish Foundation for Cardiovascular Research, Helsinki, Finland. Dr. Kunutsor acknowledges support from the NIHR Biomedical Research Centre at University Hospitals Bristol NHS Foundation Trust and the University of Bristol. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health and Social Care.


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

CC BY 4.0
Except where otherwise noted, this item's license is described as CC BY 4.0