Physical activity and risk of atrial fibrillation in the general population : meta-analysis of 23 cohort studies involving about 2 million participants
Kunutsor, S. K., Seidu, S., Mäkikallio, T. H., Dey, R. S., & Laukkanen, J. A. (2021). Physical activity and risk of atrial fibrillation in the general population : meta-analysis of 23 cohort studies involving about 2 million participants. European Journal of Epidemiology, 36(3), 259-274. https://doi.org/10.1007/s10654-020-00714-4
Julkaistu sarjassa
European Journal of EpidemiologyTekijät
Päivämäärä
2021Tekijänoikeudet
© The Author(s) 2021
Regular physical activity is well established to be associated with reduced risk of cardiovascular disease outcomes. Whether physical activity is associated with the future risk of atrial fibrillation (AF) remains a controversy. Using a systematic review and meta-analysis of published observational cohort studies in general populations with at least one-year of follow-up, we aimed to evaluate the association between regular physical activity and the risk of AF. Relevant studies were sought from inception until October 2020 in MEDLINE, Embase, Web of Science, and manual search of relevant articles. Extracted relative risks (RRs) with 95% confidence intervals (CIs) for the maximum versus the minimal amount of physical activity groups were pooled using random-effects meta-analysis. Quality of the evidence was assessed by GRADE. A total of 23 unique observational cohort studies comprising of 1,930,725 participants and 45,839 AF cases were eligible. The pooled multivariable-adjusted RR (95% CI) for AF comparing the most physically active versus the least physically active groups was 0.99 (0.93–1.05). This association was modified by sex: an increased risk was observed in men: 1.20 (1.02–1.42), with a decreased risk in women: 0.91 (0.84–0.99). The quality of the evidence ranged from low to moderate. Pooled observational cohort studies suggest that the absence of associations reported between regular physical activity and AF risk in previous general population studies and their aggregate analyses could be driven by a sex-specific difference in the associations – an increased risk in men and a decreased risk in women.
...
![showless](/themes/JYX2//images/showless.png)
![showmore](/themes/JYX2//images/showmore.png)
Julkaisija
SpringerISSN Hae Julkaisufoorumista
0393-2990Asiasanat
Julkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/47881226
Metadata
Näytä kaikki kuvailutiedotKokoelmat
- Liikuntatieteiden tiedekunta [3048]
Lisätietoja rahoituksesta
This study was supported by the NIHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol (BRC-1215–20011). The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. THM acknowledges support from the Division of Cardiology, Department of Internal Medicine, Oulu University Hospital, Oulu, Finland via the Finnish Governmental Research Funding (VTR) and the Päivikki and Sakari Solhberg Foundation.![showless](/themes/JYX2//images/showless.png)
![showmore](/themes/JYX2//images/showmore.png)
Lisenssi
Samankaltainen aineisto
Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.
-
Physical activity reduces the risk of pneumonia : systematic review and meta-analysis of 10 prospective studies involving 1,044,492 participants
Kunutsor, Setor K.; Seidu, Samuel; Laukkanen, Jari A. (Springer Science and Business Media LLC, 2022)The beneficial effects of regular physical activity in promoting health and preventing chronic diseases are well documented. The relationship between regular physical activity and the risk of pneumonia is uncertain. We ... -
Physical activity and risk of venous thromboembolism : systematic review and meta-analysis of prospective cohort studies
Kunutsor, Setor K.; Mäkikallio, Timo H.; Seidu, Samuel; de Araújo, Claudio Gil Soares; Dey, Richard S.; Blom, Ashley W.; Laukkanen, Jari A. (Springer, 2020)The inverse association between physical activity and arterial thrombotic disease is well established. Evidence on the association between physical activity and venous thromboembolism (VTE) is divergent. We conducted a ... -
Dementia in former amateur and professional contact sports participants : population-based cohort study, systematic review, and meta-analysis
Batty, G. David; Frank, Philipp; Kujala, Urho M.; Sarna, Seppo J.; Valencia-Hernández, Carlos A.; Kaprio, Jaakko (Elsevier, 2023)Background Although there is growing evidence that former professional athletes from sports characterised by repetitive head impact subsequently experience an elevated risk of dementia, the occurrence of this disorder in ... -
Suicide and depression in former contact sports participants : population-based cohort study, systematic review, and meta-analysis
Batty, G. David; Frank, Philipp; Kujala, Urho M.; Sarna, Seppo J.; Kaprio, Jaakko (Elsevier BV, 2023)Background Former participants in sports characterised by low intensity repetitive head impact appear to have elevated rates of later dementia, but links with other psychological health outcomes such as depression and ... -
Physical activity as a protective factor for dementia and Alzheimer’s disease : systematic review, meta-analysis and quality assessment of cohort and case-control studies
Iso-Markku, Paula; Kujala, Urho M; Knittle, Keegan; Polet, Juho; Vuoksimaa, Eero; Waller, Katja (BMJ Publishing Group, 2022)OBJECTIVE - Physical activity (PA) is associated with a decreased incidence of dementia, but much of the evidence comes from short follow-ups prone to reverse causation. This meta-analysis investigates the effect of study ...
Ellei toisin mainittu, julkisesti saatavilla olevia JYX-metatietoja (poislukien tiivistelmät) saa vapaasti uudelleenkäyttää CC0-lisenssillä.