The Associations of Activity Fragmentation with Physical and Mental Fatigability among Community-Dwelling 75-, 80- and 85-Year-Old People

Abstract
Background Fatigue related to task standardized by duration and intensity, termed fatigability, could manifest as shortening of activity bouts throughout the day causing daily activity to accumulate in a more fragmented pattern. Our purpose was to study the association of activity fragmentation with physical and mental dimensions of fatigability. Methods A cross-sectional study of 485 community-dwelling 75-,80- and 85-year-old people using a thigh-worn accelerometer for 3 to 7 days. Activity fragmentation was studied as Active-to-Sedentary Transition Probability (ASTP) for two operational definitions of physical activity: accelerations equivalent to at least light physical activity, and for upright posture. Physical fatigability was assessed as perceived exertion fatigability, performance fatigability severity, and with the Physical Fatigue Subscale of the Situational Fatigue Scale (SFS). Mental fatigability was assessed with the Mental Fatigue Subscale of the SFS and as a decrease in perceived mental alertness after a six-minute walk test (6MWT). Results Higher activity fragmentation was associated with higher self-reported physical fatigability, perceived exertion fatigability and performance fatigability severity, independent of total activity minutes (β 0.13-0.33, p<0.05 for all). Higher activity fragmentation was not associated with mental fatigability in the fully adjusted models. The associations with fatigability indices were similar for both activity fragmentation indicators. Associations of activity fragmentation and performance fatigability severity were similar also among those with the highest intensity-based physical activity volume. Conclusions The findings provide support that studying fragmented activity patterns can be useful in identifying those at risk for high fatigability, even among those with relatively high physical activity level.
Main Authors
Format
Articles Research article
Published
2020
Series
Subjects
Publication in research information system
Publisher
Oxford University Press (OUP)
The permanent address of the publication
https://urn.fi/URN:NBN:fi:jyu-202007065244Use this for linking
Review status
Peer reviewed
ISSN
1079-5006
DOI
https://doi.org/10.1093/gerona/glaa166
Language
English
Published in
Journals of Gerontology Series A : Biological Sciences and Medical Sciences
Citation
  • Palmberg, L., Rantalainen, T., Rantakokko, M., Karavirta, L., Siltanen, S., Skantz, H., Saajanaho, M., Portegijs, E., & Rantanen, T. (2020). The Associations of Activity Fragmentation with Physical and Mental Fatigability among Community-Dwelling 75-, 80- and 85-Year-Old People. Journals of Gerontology Series A : Biological Sciences and Medical Sciences, 75(9), e103-e110. https://doi.org/10.1093/gerona/glaa166
License
In CopyrightOpen Access
Funder(s)
Research Council of Finland
European Commission
Research Council of Finland
Funding program(s)
Academy Research Fellow, AoF
ERC European Research Council, H2020
Research costs of Academy Research Fellow, AoF
Akatemiatutkija, SA
ERC European Research Council, H2020
Akatemiatutkijan tutkimuskulut, SA
Research Council of FinlandEuropean CommissionEuropean research council
Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Education and Culture Executive Agency (EACEA). Neither the European Union nor EACEA can be held responsible for them.
Additional information about funding
This work was supported by the European Research Council (grant number 693045 [to TaR]); the Academy of Finland (grant numbers 321336 and 328818 [to TiR], grant number 310526 [to TaR]); the Finnish Ministry of Education and Culture [to MR and EP] and the University of Jyvaskyla.
Copyright© The Author(s) 2020

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