Physical Inactivity from Youth to Adulthood and Risk of Impaired Glucose Metabolism
Kallio, P., Pahkala, K., Heinonen, O. J., Tammelin, T., Hirvensalo, M., Telama, R., Juonala, M., Magnussen, C. G., Rovio, S., Helajärvi, H., Hutri-Kähönen, N., Viikari, J., & Raitakari, O. T. (2018). Physical Inactivity from Youth to Adulthood and Risk of Impaired Glucose Metabolism. Medicine and Science in Sports and Exercise, 50(6), 1192-1198. https://doi.org/10.1249/MSS.0000000000001555
Published inMedicine and Science in Sports and Exercise
© 2018 by the American College of Sports Medicine
INTRODUCTION: Physical activity (PA) is important in the prevention and treatment of impaired glucose metabolism. However, association of physical inactivity during the transition between childhood and adulthood with glucose metabolism is unknown. Therefore, we studied the association of persistent physical inactivity since childhood with glucose metabolism in adulthood. METHODS: Data were drawn from the ongoing, Cardiovascular Risk in Young Finns Study with repeated follow-ups between 1980 and 2011 (baseline age, 3-18 yr; n = 3596). Impaired glucose metabolism was defined as having impaired fasting glucose (6.1-6.9 mmol·L) or type 2 diabetes in adulthood. Leisure-time PA habits were repeatedly collected with a standardized questionnaire and expressed as a PA Index. Using PA Index, four groups were formed (n = 2000): 1) persistently low PA, 2) decreasingly active, 3) increasingly active, and 4) persistently active subjects. Poisson regression model was used to examine the association between PA groups and impaired glucose metabolism. RESULTS: The proportion of the sample with impaired glucose metabolism was 16.1% in individuals with persistently low PA, 14.5% in decreasingly active, 6.8% in increasingly active, and 11.1% in persistently active. Compared with individuals with persistently low PA, age and sex-adjusted risk for impaired glucose metabolism were lower in those who increased PA (relative risk [RR], 0.47; 95% confidence interval [CI], 0.29-0.76) and in those who were persistently active (RR, 0.70; 95% CI, 0.51-0.97), but similar in those who decreased PA (RR, 0.93; 95% CI, 0.66-1.36). CONCLUSIONS: Persistently physically inactive lifestyle from youth to adulthood is associated with increased risk of impaired glucose metabolism in adulthood. Importantly, a moderate increase in PA lowered the risk. The results highlight the importance of avoiding physically inactive lifestyle at all stages of life. ...
PublisherLippincott Williams & Wilkins; American College of Sports Medicine
Publication in research information system
MetadataShow full item record
- Liikuntatieteiden tiedekunta 
Showing items with similar title or keywords.
The effects of physical activity and diet change on intracellular lipids and metabolism in mice with diet-induced obesity Rinnankoski-Tuikka, Rita (University of Jyväskylä, 2014)
Liikunnallisuus ja hyvä kunto ehkäisevät tyypin 2 diabetesta ja valtimotautien riskitekijöitä lapsesta lähtien Väistö, Juuso; Haapala, Eero; Lakka, Timo A. (Liikuntatieteellinen seura, 2021)Lasten ylipaino on saavuttanut epidemian mittasuhteet maailmanlaajuisesti. Vaikka viime vuosina tilanne on hiukan parantunut, ylipaino on edelleen yksi merkittävimmistä kansanterveydellisistä ongelmista. Riskitekijöiden ...
Kaseva, Kaisa; Lounassalo, Irinja; Yang, Xiaolin; Kukko, Tuomas; Hakonen, Harto; Kulmala, Janne; Pahkala, Katja; Rovio, Suvi; Hirvensalo, Mirja; Raitakari, Olli; Tammelin, Tuija H.; Salin, Kasper (Nature Publishing Group, 2023)This study examined whether active commuting to school in childhood and adolescence predicted active commuting to work and overall physical activity (PA) in adulthood. Participants from the Young Finns Study (N = 2436) ...
Towards early risk biomarkers : serum metabolic signature in childhood predicts cardio-metabolic risk in adulthood Ojanen, Xiaowei; Cheng, Runtan; Törmäkangas, Timo; Rappaport, Noa; Wilmanski, Tomasz; Wu, Na; Fung, Erik; Nedelec, Rozenn; Sebert, Sylvain; Vlachopoulos, Dimitris; Yan, Wei; Price, Nathan D.; Cheng, Sulin; Wiklund, Petri (Elsevier, 2021)Background Cardiovascular diseases may originate in childhood. Biomarkers identifying individuals with increased risk for disease are needed to support early detection and to optimise prevention strategies. Methods In ...
Does organized sport participation during youth predict healthy habits in adulthood? : A 28-year longitudinal study Palomäki, Sanna; Hirvensalo, Mirja; Smith, Kylie; Raitakari, Olli; Männistö, Satu; Hutri-Kähönen, Nina; Tammelin, Tuija (Wiley-Blackwell Publishing Ltd., 2018)Health behaviors in youth can predict the same behaviors later in life, but the role of sport participation in predicting healthy lifestyle habits is unclear. This study aimed to investigate the association between ...