dc.contributor.author | van Bijnen, Sam | |
dc.contributor.author | Kärkkäinen, Salme | |
dc.contributor.author | Helenius, Päivi | |
dc.contributor.author | Parviainen, Tiina | |
dc.date.accessioned | 2019-07-03T05:01:54Z | |
dc.date.available | 2019-07-03T05:01:54Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | van Bijnen, S., Kärkkäinen, S., Helenius, P., & Parviainen, T. (2019). Left hemisphere enhancement of auditory activation in language impaired children. <i>Scientific Reports</i>, <i>9</i>, Article 9087. <a href="https://doi.org/10.1038/s41598-019-45597-y" target="_blank">https://doi.org/10.1038/s41598-019-45597-y</a> | |
dc.identifier.other | CONVID_31253207 | |
dc.identifier.other | TUTKAID_81820 | |
dc.identifier.uri | https://jyx.jyu.fi/handle/123456789/64970 | |
dc.description.abstract | Specific language impairment (SLI) is a developmental disorder linked to deficient auditory processing. In this magnetoencephalography (MEG) study we investigated a specific prolonged auditory response (N250m) that has been reported predominantly in children and is associated with level of language skills. We recorded auditory responses evoked by sine-wave tones presented alternately to the right and left ear of 9–10-year-old children with SLI (n = 10) and children with typical language development (n = 10). Source analysis was used to isolate the N250m response in the left and right hemisphere. In children with language impairment left-hemisphere N250m responses were enhanced compared to those of controls, while no group difference was found in the right hemisphere. Consequently, language impaired children lacked the typical right-ward asymmetry that was found in control children. Furthermore, left but not right hemisphere N250m responses correlated positively with performance on a phonological processing task in the SLI group exclusively, possibly signifying a compensatory mechanism for delayed maturation of language processing. These results suggest that enhanced left-hemisphere auditory activation reflects a core neurophysiological manifestation of developmental language disorders, and emphasize the relevance of this developmentally specific activation pattern for competent language development. | fi |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | |
dc.publisher | Nature Publishing Group | |
dc.relation.ispartofseries | Scientific Reports | |
dc.rights | CC BY 4.0 | |
dc.subject.other | sensory processing | |
dc.subject.other | specific language impartment | |
dc.subject.other | auditory response | |
dc.title | Left hemisphere enhancement of auditory activation in language impaired children | |
dc.type | article | |
dc.identifier.urn | URN:NBN:fi:jyu-201907023545 | |
dc.contributor.laitos | Matematiikan ja tilastotieteen laitos | fi |
dc.contributor.laitos | Psykologian laitos | fi |
dc.contributor.laitos | Department of Mathematics and Statistics | en |
dc.contributor.laitos | Department of Psychology | en |
dc.contributor.oppiaine | Tilastotiede | fi |
dc.contributor.oppiaine | Psykologia | fi |
dc.contributor.oppiaine | Monitieteinen aivotutkimuskeskus | fi |
dc.contributor.oppiaine | Hyvinvoinnin tutkimuksen yhteisö | fi |
dc.contributor.oppiaine | Statistics | en |
dc.contributor.oppiaine | Psychology | en |
dc.contributor.oppiaine | Centre for Interdisciplinary Brain Research | en |
dc.contributor.oppiaine | School of Wellbeing | en |
dc.type.uri | http://purl.org/eprint/type/JournalArticle | |
dc.date.updated | 2019-07-02T12:15:16Z | |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
dc.description.reviewstatus | peerReviewed | |
dc.relation.issn | 2045-2322 | |
dc.relation.numberinseries | 0 | |
dc.relation.volume | 9 | |
dc.type.version | publishedVersion | |
dc.rights.copyright | © The Authors, 2019. | |
dc.rights.accesslevel | openAccess | fi |
dc.relation.grantnumber | 641652 | |
dc.relation.grantnumber | 641652 | |
dc.relation.projectid | info:eu-repo/grantAgreement/EC/H2020/641652/EU//ChildBrain | |
dc.subject.yso | neurofysiologia | |
dc.subject.yso | kehityksellinen kielihäiriö | |
dc.subject.yso | kuulo | |
dc.format.content | fulltext | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p2316 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p12073 | |
jyx.subject.uri | http://www.yso.fi/onto/yso/p1937 | |
dc.rights.url | https://creativecommons.org/licenses/by/4.0/ | |
dc.relation.doi | 10.1038/s41598-019-45597-y | |
dc.relation.funder | Euroopan komissio | fi |
dc.relation.funder | European Commission | en |
jyx.fundingprogram | MSCA Marie Skłodowska-Curie Actions, H2020 | fi |
jyx.fundingprogram | MSCA Marie Skłodowska-Curie Actions, H2020 | en |
dc.type.okm | A1 | |