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Human HDL subclasses modulate energy metabolism in skeletal muscle cells
Lund, Jenny; Lähteenmäki, Emilia; Eklund, Tiia; Bakke, Hege G.; Thoresen, G. Hege; Pirinen, Eija; Jauhiainen, Matti; Rustan, Arild C.; Lehti, Maarit (Elsevier, 2024)In addition to its anti-atherogenic role, HDL reportedly modulates energy metabolism at the whole-body level. HDL functionality is associated with its structure and composition, and functional activities can differ between ... -
Resistance exercise with different workloads have distinct effects on cellular respiration of peripheral blood mononuclear cells
Lähteenmäki, Emilia Ilona; Koski, Max; Koskela, Iida; Lehtonen, Elias; Kankaanpää, Anna; Kainulainen, Heikki; Walker, Simon; Lehti, Maarit (Wiley, 2022)Little is known how acute exercise-induced inflammation and metabolic stress affect immune cell bioenergetics and the portion of its components. Therefore, we investigated acute effects of eccentric-only (E), concentric-only ... -
The metabolic responses to electrical pulse-induced contractions in C2C12 myotubes are greater in high glucose medium
Mäntyselkä, Sakari (2021)Osaa liikunnan terveyshyötyjen mekanismeista on vaikeaa tutkia ihmisillä tai koe-eläimillä. Viljeltyjen C2C12 myotuubien sähköpulssistimulaatiolla (EPS, engl. electrical pulse stimulation) voidaan mallintaa lihassupistuksia ... -
The relationship between mitochondrial respiration, resting metabolic rate and blood cell count in great tits
Thoral, Elisa; García-Díaz, Carmen C.; Persson, Elin; Chamkha, Imen; Elmér, Eskil; Ruuskanen, Suvi; Nord, Andreas (The Company of Biologists, 2024)Although mitochondrial respiration is believed to explain a substantial part of the variation in resting metabolic rate (RMR), few studies have empirically studied the relationship between organismal and cellular metabolism. ... -
Branched-Chain Amino Acid Levels Are Related with Surrogates of Disturbed Lipid Metabolism among Older Men
Kujala, Urho; Peltonen, Markku; Laine, Merja K.; Kaprio, Jaakko; Heinonen, Olli. J.; Sundvall, Jouko; Eriksson, Johan G.; Jula, Antti; Sarna, Seppo; Kainulainen, Heikki (Frontiers Research Foundation, 2016)Aims/hypothesis: Existing studies suggest that decreased branched-chain amino acid (BCAA) catabolism and thus elevated levels in blood are associated with metabolic disturbances. Based on such information, we have developed ...