Prioritizing covariates in the planning of future studies in the meta-analytic framework
Karvanen, J., & Sillanpää, M. J. (2017). Prioritizing covariates in the planning of future studies in the meta-analytic framework. Biometrical Journal, 59(1), 110-125. https://doi.org/10.1002/bimj.201600067
Published inBiometrical Journal
© 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim.
Science can be seen as a sequential process where each new study augments evidence to the existing knowledge. To have the best prospects to make an impact in this process, a new study should be designed optimally taking into account the previous studies and other prior information. We propose a formal approach for the covariate prioritization, i.e., the decision about the covariates to be measured in a new study. The decision criteria can be based on conditional power, change of the p-value, change in lower confidence limit, Kullback-Leibler divergence, Bayes factors, Bayesian false discovery rate or difference between prior and posterior expectation. The criteria can be also used for decisions on the sample size. As an illustration, we consider covariate prioritization based on genome-wide association studies for C-reactive protein levels and make suggestions on the genes to be studied further.
PublisherWiley - VCH Verlag GmbH & Co. KGaA
Publication in research information system
MetadataShow full item record
Showing items with similar title or keywords.
Using meta-analytic path analysis to test theoretical predictions in health behavior: An illustration based on meta-analyses of the theory of planned behavior Hagger, Martin; Chan, Dervin K. C.; Protogerou, Cleo; Chatzisarantis, Nikos L. D. (Academic Press; American Society of Preventive Oncology, 2016)Objective Synthesizing research on social cognitive theories applied to health behavior is an important step in the development of an evidence base of psychological factors as targets for effective behavioral interventions. ...
Kalaja, Paula; Pitkänen-Huhta, Anne (De Gruyter Mouton, 2018)This introductory article serves two purposes. Firstly, it provides the background for the set of 11 articles that appear in the special issue of this journal and summarizes the articles along a number of dimensions. All ...
Halonen, Vilho (2021)Tässä tutkielmassa verrataan analyyttisien menetelmien ja koneoppimismallien toimivuutta epätarkkuudesta johtuvien virheiden kontrolloinnissa. Tarkasteltavana matemaattisena esimerkkiongelmana käytetään lineaarista ...
The reasoned action approach applied to health behavior : Role of past behavior and tests of some key moderators using meta-analytic structural equation modeling Hagger, Martin; Polet, Juho; Lintunen, Taru (Pergamon Press, 2018)Rationale The reasoned action approach (RAA) is a social cognitive model that outlines the determinants of intentional behavior. Primary and meta-analytic studies support RAA predictions for multiple health behaviors. ...
Aaltio, Iiris; Wang, Qian (International Council for Small Business, 2016)In this study, we explore how extant literature contributes to the development in women entrepreneurship research in terms of both theoretical and practical perspectives. Accordingly, an ostensible tendency can be seen ...