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dc.contributor.authorIjäs, Heini
dc.contributor.authorNummelin, Sami
dc.contributor.authorShen, Boxuan
dc.contributor.authorKostiainen, Mauri A.
dc.contributor.authorLinko, Veikko
dc.date.accessioned2018-08-16T05:23:22Z
dc.date.available2018-08-16T05:23:22Z
dc.date.issued2018
dc.identifier.citationIjäs, H., Nummelin, S., Shen, B., Kostiainen, M. A., & Linko, V. (2018). Dynamic DNA Origami Devices : from Strand-Displacement Reactions to External-Stimuli Responsive Systems. <i>International Journal of Molecular Sciences</i>, <i>19</i>(7), Article 2114. <a href="https://doi.org/10.3390/ijms19072114" target="_blank">https://doi.org/10.3390/ijms19072114</a>
dc.identifier.otherCONVID_28207514
dc.identifier.otherTUTKAID_78507
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/59260
dc.description.abstractDNA nanotechnology provides an excellent foundation for diverse nanoscale structures that can be used in various bioapplications and materials research. Among all existing DNA assembly techniques, DNA origami proves to be the most robust one for creating custom nanoshapes. Since its invention in 2006, building from the bottom up using DNA advanced drastically, and therefore, more and more complex DNA-based systems became accessible. So far, the vast majority of the demonstrated DNA origami frameworks are static by nature; however, there also exist dynamic DNA origami devices that are increasingly coming into view. In this review, we discuss DNA origami nanostructures that exhibit controlled translational or rotational movement when triggered by predefined DNA sequences, various molecular interactions, and/or external stimuli such as light, pH, temperature, and electromagnetic fields. The rapid evolution of such dynamic DNA origami tools will undoubtedly have a significant impact on molecular-scale precision measurements, targeted drug delivery and diagnostics; however, they can also play a role in the development of optical/plasmonic sensors, nanophotonic devices, and nanorobotics for numerous different tasks.fi
dc.format.mimetypeapplication/pdf
dc.language.isoeng
dc.publisherMDPI
dc.relation.ispartofseriesInternational Journal of Molecular Sciences
dc.rightsCC BY 4.0
dc.subject.otherDNA nanotechnology
dc.subject.otherDNA origami
dc.subject.otherself-assembly
dc.subject.othermolecular devices
dc.subject.othermechanical movement
dc.titleDynamic DNA Origami Devices : from Strand-Displacement Reactions to External-Stimuli Responsive Systems
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201808133821
dc.contributor.laitosBio- ja ympäristötieteiden laitosfi
dc.contributor.laitosDepartment of Biological and Environmental Scienceen
dc.contributor.oppiaineSolu- ja molekyylibiologiafi
dc.contributor.oppiaineNanoscience Centerfi
dc.contributor.oppiaineCell and Molecular Biologyen
dc.contributor.oppiaineNanoscience Centeren
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2018-08-13T12:15:19Z
dc.type.coarhttp://purl.org/coar/resource_type/c_dcae04bc
dc.description.reviewstatuspeerReviewed
dc.relation.issn1661-6596
dc.relation.numberinseries7
dc.relation.volume19
dc.type.versionpublishedVersion
dc.rights.copyright© the Authors, 2018.
dc.rights.accesslevelopenAccessfi
dc.subject.ysonanotekniikka
dc.subject.ysoDNA
dc.subject.ysorobotiikka
dc.format.contentfulltext
jyx.subject.urihttp://www.yso.fi/onto/yso/p11463
jyx.subject.urihttp://www.yso.fi/onto/yso/p7690
jyx.subject.urihttp://www.yso.fi/onto/yso/p2615
dc.rights.urlhttps://creativecommons.org/licenses/by/4.0/
dc.relation.doi10.3390/ijms19072114
dc.type.okmA2


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