Objectively measured physical activity profile and cognition in Finnish elderly twins
Iso-Markku, P., Waller, K., Vuoksimaa, E., Vähä-Ypyä, H., Lindgren, N., Heikkilä, K., Sievänen, H., Rinne, J., Kaprio, J., & Kujala, U. (2018). Objectively measured physical activity profile and cognition in Finnish elderly twins. Alzheimer's and Dementia : Translational Research and Clinical Interventions, 4, 263-271. https://doi.org/10.1016/j.trci.2018.06.007
© 2018 The Authors. Published by Elsevier Inc. on behalf of the Alzheimer’s Association.
Introduction: We studied whether objectively measured physical activity (PA) and sedentary behavior (SB) are associated with cognition in Finnish elderly twins. Methods: This cross-sectional study comprised twins born in Finland from 1940 to 1944 in the Older Finnish Twin Cohort (mean age, 72.9 years; 726 persons). From 2014 to 2016, cognition was assessed with a validated telephonic interview, whereas PA was measured with a waist-worn accelerometer. Results: In between-family models, SB and light physical activity had significant linear associations with cognition after adjusting for age, sex, wearing time, education level, body mass index, and living condition (SB: b-estimate, 20.21 [95% confidence intervals, 20.42 to 20.003]; light physical activity: b-estimate, 0.30 [95% confidence intervals, 0.02–0.58]). In within-family models, there were no significant linear associations between objectively measured PA and cognition. Discussion: Objectively measured light physical activity and SB are associated with cognition in Finnish twins in their seventies, but the associations were attributable to genetic and environmental selection. ...
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