Normal-weight obesity and cardiometabolic risk : A 7-year longitudinal study in girls from prepuberty to early adulthood
Wiklund, P., Törmäkangas, T., Shi, Y., Wu, N., Vainionpää, A., Alen, M., & Cheng, S. (2017). Normal-weight obesity and cardiometabolic risk : A 7-year longitudinal study in girls from prepuberty to early adulthood. Obesity, 25(6), 1077-1082. https://doi.org/10.1002/oby.21838
Shi, Yi |
Wu, Na |
DisciplineLiikuntalääketiedeGerontologia ja kansanterveysSports and Exercise MedicineGerontology and Public Health
© John Wiley & Sons, 2017. This is a final draft version of an article whose final and definitive form has been published by Wiley. Published in this repository with the kind permission of the publisher.
Objective: To study whether normal-weight obesity in childhood is associated with increased cardiometabolic risk in early adulthood. Methods: This study assessed data for 236 girls followed from prepuberty to early adulthood. Growth chart data were obtained from birth to 18 years. Body composition was assessed by dual-energy x-ray absorptiometry and cardiometabolic risk by calculating continuous clustered risk score (at ages 11, 14, and 18). The association of body weight status with cardiometabolic risk from childhood to early adulthood was examined. Results: Subjects with normal-weight obesity were virtually indistinguishable from their normal-weight lean peers in terms of relative body weight and BMI but had significantly higher fat mass (7.1-7.3 kg) and cardiometabolic risk already in childhood, and this difference persisted into early adulthood (P < 0.001 for all). Conclusions: Children and adolescents with normal body weight and high body fat percentage may be at increased risk for cardiometabolic morbidity in adulthood. Body fatness may be of utility in clinical practice to effectively identify children and adolescents at risk and to permit recommendation of lifestyle changes that could translate to lower risks of cardiovascular diseases in the future. ...
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Additional information about fundingThis work was supported financially by the Academy of Finland, the Ministry of Education of Finland, the University of Jyväskylä, the China State Sport General Administration (Grant 2013B040), the National Nature Science Foundation of China (Grant 31571219), the Shanghai Jiao Tong University Zhiyuan Foundation (Grant CP2014013), and EVO research grants (years 2012/2013) from Oulu University Hospital. The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. ...
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