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dc.contributor.authorReijnierse, E. M.
dc.contributor.authorTrappenburg, M. C.
dc.contributor.authorLeter, M. J.
dc.contributor.authorSipilä, Sarianna
dc.contributor.authorStenroth, Lauri
dc.contributor.authorNarici, M. V.
dc.contributor.authorHogrel, J. Y.
dc.contributor.authorButler-Browne, G.
dc.contributor.authorMcPhee, J. S.
dc.contributor.authorPääsuke, M.
dc.contributor.authorGapeyeva, H.
dc.contributor.authorMeskers, C. G. M.
dc.contributor.authorMaier, A. B.
dc.date.accessioned2015-11-24T07:10:26Z
dc.date.available2015-11-24T07:10:26Z
dc.date.issued2015
dc.identifier.citationReijnierse, E. M., Trappenburg, M. C., Leter, M. J., Sipilä, S., Stenroth, L., Narici, M. V., Hogrel, J. Y., Butler-Browne, G., McPhee, J. S., Pääsuke, M., Gapeyeva, H., Meskers, C. G. M., & Maier, A. B. (2015). Serum albumin and muscle measures in a cohort of healthy young and old participants. <i>AGE</i>, <i>37</i>(5), Article 88. <a href="https://doi.org/10.1007/s11357-015-9825-6" target="_blank">https://doi.org/10.1007/s11357-015-9825-6</a>
dc.identifier.otherCONVID_24860049
dc.identifier.otherTUTKAID_66985
dc.identifier.urihttps://jyx.jyu.fi/handle/123456789/47788
dc.description.abstractConsensus on clinically valid diagnostic criteria for sarcopenia requires a systematical assessment of the association of its candidate measures of muscle mass, muscle strength, and physical performance on one side and muscle-related clinical parameters on the other side. In this study, we systematically assessed associations between serum albumin as a muscle-related parameter and muscle measures in 172 healthy young (aged 18–30 years) and 271 old participants (aged 69–81 year) from the European MYOAGE study. Muscle measures included relative muscle mass, i.e., total- and appendicular lean mass (ALM) percentage, absolute muscle mass, i.e., ALM/height2 and total lean mass in kilograms, handgrip strength, and walking speed. Muscle measures were standardized and analyzed in multivariate linear regression models, stratified by age. Adjustment models included age, body composition, C-reactive protein and lifestyle factors. In young participants, serum albumin was positively associated with lean mass percentage (p = 0.007) and with ALM percentage (p = 0.001). In old participants, serum albumin was not associated with any of the muscle measures. In conclusion, the association between serum albumin and muscle measures was only found in healthy young participants and the strongest for measures of relative muscle mass.
dc.language.isoeng
dc.publisherSpringer International Publishing; American Aging Association
dc.relation.ispartofseriesAGE
dc.subject.otherSarcopenia
dc.subject.otherSerum albumin
dc.titleSerum albumin and muscle measures in a cohort of healthy young and old participants
dc.typearticle
dc.identifier.urnURN:NBN:fi:jyu-201511203757
dc.contributor.laitosLiikuntabiologian laitosfi
dc.contributor.laitosTerveystieteiden laitosfi
dc.contributor.laitosDepartment of Biology of Physical Activityen
dc.contributor.laitosDepartment of Health Sciencesen
dc.contributor.oppiaineBiomekaniikkafi
dc.contributor.oppiaineGerontologia ja kansanterveysfi
dc.contributor.oppiaineBiomechanicsen
dc.contributor.oppiaineGerontology and Public Healthen
dc.type.urihttp://purl.org/eprint/type/JournalArticle
dc.date.updated2015-11-20T16:15:12Z
dc.type.coarjournal article
dc.description.reviewstatuspeerReviewed
dc.relation.issn1574-4647
dc.relation.numberinseries5
dc.relation.volume37
dc.type.versionpublishedVersion
dc.rights.copyright© The Author(s) 2015. This article is published with open access at Springerlink.com.
dc.rights.accesslevelopenAccessfi
dc.subject.ysolihasmassa
dc.subject.ysolihasvoima
jyx.subject.urihttp://www.yso.fi/onto/yso/p29135
jyx.subject.urihttp://www.yso.fi/onto/yso/p23362
dc.relation.doi10.1007/s11357-015-9825-6


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