Impaired geometric properties of tibia in older women with hip fracture history

Abstract
Introduction The purpose of this study was to evaluate side-to-side differences in tibial mineral mass and geometry after hip fracture, and to assess the determinants of such differences. Methods Thirty-eight 60- to 85-year-old women with a previous hip fracture and twenty-two same-aged control women without fractures participated in the study. Bone characteristics of the distal tibia and tibial shaft of both legs were assessed using pQCT in order to compare the side-to-side differences of tibias between the two groups. Results The subjects with fracture history had significantly (p≤0.05, analysis of covariance) larger side-to-side differences than the controls in tibial shaft BMC (-4.9% vs. -0.5%), cortical area (-5.2% vs. 0.1%) and polar moment of inertia (Ipolar) (-5.6% vs. -0.8%) and in distal tibia BMC (-5.1% vs. -1.4%) and Ipolar (-7.5% vs. -2.4%). In the fracture patients, the side-to-side differences in muscle characteristics explained 23 to 44% of the variances in the side-to-side differences in bone mass and geometry. Conclusions Hip fracture results in reduced bone mass and impaired bone geometry in the tibia of the affected limb in older women. Muscle-induced loading may have a considerable role in the recovery of bone mineral mass and geometry after hip fracture.
Main Authors
Format
Articles Research article
Published
2007
Series
Subjects
Publication in research information system
The permanent address of the publication
https://urn.fi/URN:NBN:fi:jyu-201411193292Use this for linking
Review status
Peer reviewed
ISSN
1433-2965
DOI
https://doi.org/10.1007/s00198-007-0352-x
Language
English
Published in
Osteoporosis International
Citation
  • Mikkola, T., Sipilä, S., Portegijs, E., Kallinen, M., Alén, M., Kiviranta, I., Pekkonen, M., & Heinonen, A. (2007). Impaired geometric properties of tibia in older women with hip fracture history. Osteoporosis International, 18(8), 1083-1090. https://doi.org/10.1007/s00198-007-0352-x
License
Open Access
Copyright© Springer (2007). This is a final draft version of an article whose final and definitive form has been published by Springer.

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