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Design and synthesis of non-peptide integrin inhibitors
DisciplineOrgaaninen kemiaOrganic Chemistry
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- Pro gradu -tutkielmat 
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Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors Islam, Mohammad Shahidul; Al-Majid, Abdullah Mohammed; Azam, Mohammad; Verma, Ved Prakash; Barakat, Assem; Haukka, Matti; Elgazar, Abdullah A.; Mira, Amira; Badria, Farid A. (American Chemical Society (ACS), 2021)Twenty-five new hits of spirooxindole analogs 8a–y engrafted with indole and pyrazole scaffolds were designed and constructed via a [3+2]cycloaddition (32CA) reaction starting from three components: new chalcone-based ...
Synthesis, X-ray Single-Crystal Analysis, and Anticancer Activity Evaluation of New Alkylsulfanyl-Pyridazino[4,5-b]indole Compounds as Multitarget Inhibitors of EGFR and Its Downstream PI3K-AKT Pathway Salama, Eid E.; Althobaiti, Ibrahim O.; Haukka, Matti; Boraei, Ahmed T. A. (MDPI AG, 2022)The alkylation of 3,5-dihydro-4H-pyridazino[4,5-b]indole-4-thione with benzyl bromide, ethyl chloroacetate, and allyl bromide in the presence of potassium carbonate (K2CO3) yielded new alkylsulfanylpyridazino[4,5-b]indole ...
Design Framework and Principles for Learning Environment Co-Design : Synthesis from Literature and Three Empirical Studies Mäkelä, Tiina; Leinonen, Teemu (MDPI AG, 2021)The need for environments conducive to learning and wellbeing has been broadly recognised. Considering particularly learner perceptions in the learning environment design is known to improve both their learning and wellbeing. ...
Crystalline forms of selected agrochemical actives : design and synthesis of cocrystals Nauha, Elisa (University of Jyväskylä, 2012)The research described in this disseration covers the crystal form screening of two analogous agrochemical actives, thiophanate-methyl and thiophanate-ethyl, as well as the discovery of seven 4-hydroxybenzoic acid ...
SMD simulation of talin and integrin interaction : role of membrane proximal and distal integrin segments in talin binding Palmujoki, Lassi (2022)Fyysisiä voimia käsittelevä molekyylibiologian alue on nopeasti kehittymässä, johtuen sekä tietokoneiden laskentakapasiteetin kasvusta että kehityksistä teoreettisilla rintamilla kuten molekyylijärjestelmien laskennallisessa ...