Isoflavones and Rotenoids from the Leaves of Millettia oblata ssp. teitensis
Deyou, T., Marco, M., Heydenreich, M., Pan, F., Gruhonjic, A., Fitzpatrick, P. A., Koch, A., Derese, S., Pelletier, J., Rissanen, K., Yenesew, A., & Erdélyi, M. (2017). Isoflavones and Rotenoids from the Leaves of Millettia oblata ssp. teitensis. Journal of Natural Products, 80(7), 2060-2066. https://doi.org/10.1021/acs.jnatprod.7b00255
Julkaistu sarjassa
Journal of Natural ProductsTekijät
Päivämäärä
2017Tekijänoikeudet
© 2017 American Chemical Society and American Society of Pharmacognosy. This is an open access article published under an ACS AuthorChoice License, which permits
copying and redistribution of the article or any adaptations for non-commercial purposes.
A new isoflavone, 8-prenylmilldrone (1), and four
new rotenoids, oblarotenoids A−D (2−5), along with nine known
compounds (6−14), were isolated from the CH2Cl2/CH3OH
(1:1) extract of the leaves of Millettia oblata ssp. teitensis by
chromatographic separation. The purified compounds were
identified by NMR spectroscopic and mass spectrometric analyses,
whereas the absolute configurations of the rotenoids were
established on the basis of chiroptical data and in some cases by
single-crystal X-ray crystallography. Maximaisoflavone J (11) and
oblarotenoid C (4) showed weak activity against the human breast
cancer cell line MDA-MB-231 with IC50 values of 33.3 and 93.8
μM, respectively.
Julkaisija
American Chemical Society; American Society of PharmacognosyISSN Hae Julkaisufoorumista
0163-3864Asiasanat
Julkaisu tutkimustietojärjestelmässä
https://converis.jyu.fi/converis/portal/detail/Publication/27106061
Metadata
Näytä kaikki kuvailutiedotKokoelmat
Lisenssi
Ellei muuten mainita, aineiston lisenssi on © 2017 American Chemical Society and American Society of Pharmacognosy. This is an open access article published under an ACS AuthorChoice License, which permits
copying and redistribution of the article or any adaptations for non-commercial purposes.
Samankaltainen aineisto
Näytetään aineistoja, joilla on samankaltainen nimeke tai asiasanat.
-
Prenylated Flavonoids from the Roots of Tephrosia rhodesica
Atilaw, Yoseph; Muiva-Mutisya, Lois; Bogaerts, Jonathan; Duffy, Sandra; Valkonen, Arto; Heydenreich, Matthias; Avery, Vicky M.; Rissanen, Kari; Erdélyi, Máté; Yenesew, Abiy (American Chemical Society (ACS), 2020)Five new compounds—rhodimer (1), rhodiflavan A (2), rhodiflavan B (3), rhodiflavan C (4), and rhodacarpin (5)—along with 16 known secondary metabolites, were isolated from the CH2Cl2–CH3OH (1:1) extract of the roots of ... -
Mukaiyama-Michael reactions with α-substituted acroleins - a useful tool for the synthesis of the pectenotoxins and other natural product targets
Kemppainen, Eeva K. (University of Jyväskylä, 2013) -
Synthetic studies on 1-azabicyclo[5.3.0]decane alkaloids
Siitonen, Juha (University of Jyväskylä, 2018)The first chapter introduces the reader to the concept of natural product total synthesis and its importance to chemistry, other sciences, and society. The second chapter reviews the chemistry of natural products ... -
Substituoitujen aryylirenkaiden ohjattu orto-litiointi ja sen hyödyntäminen valterioni C:n kokonaissynteesissä
Taskinen, Elina (2020)Tämän Pro Gradu -tutkielman kirjallinen osa käsittelee ohjattua orto-litiointia ja sen sovel-luksia orgaanisessa synteesikemiassa. Lähtöaineiden kohdalla aihe on rajattu koskemaan substituoituja aryylirenkaita, kun taas ... -
Formal synthesis of ent-Cephalotaxine using a one-pot Parham-aldol sequence
Siitonen, Juha; Yu, Lu; Danielsson, Jakob; Gregorio, Giovanni Di; Somfai, Peter (American Chemical Society, 2018)A short formal synthesis of ent-Cephalotaxine is achieved. The approach features a new Lewis acid mediated [2,3]-Stevens rearrangement of N-allylated prolineamide to generate a key quaternary stereogenic center. Additionally, ...
Ellei toisin mainittu, julkisesti saatavilla olevia JYX-metatietoja (poislukien tiivistelmät) saa vapaasti uudelleenkäyttää CC0-lisenssillä.