Structural analysis of two foldamer-type oligoamides the effect of hydrogen bonding on solvate formation, crystal structures and molecular conformation

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dc.contributor.author Suhonen, Aku
dc.contributor.author Nauha, Elisa
dc.contributor.author Salorinne, Kirsi
dc.contributor.author Helttunen, Kaisa
dc.contributor.author Nissinen, Maija
dc.date.accessioned 2012-12-04T09:50:32Z
dc.date.available 2013-08-17T21:45:03Z
dc.date.issued 2012 fi
dc.identifier.citation Suhonen, A., Nauha, E., Salorinne, K., Helttunen, K., & Nissinen, M. (2012). Structural analysis of two foldamer-type oligoamides the effect of hydrogen bonding on solvate formation, crystal structures and molecular conformation. CrystEngComm, 14 (21), 7398-7407. doi:10.1039/c2ce25981h Retrieved from http://pubs.rsc.org/en/content/articlelanding/2012/ce/c2ce25981h#!divAbstract fi
dc.identifier.issn 1466-8033
dc.identifier.other TUTKAID_52296
dc.identifier.uri http://hdl.handle.net/123456789/40524
dc.description Author's Final draft
dc.description.abstract The crystal structures and molecular conformations of two foldamer-type oligoamides were analyzed. One polymorphic form and seven solvates were found for N¹,N³-bis(2-benzamidophenyl)benzene-1,3-dicarboxamide (the benzene variant), and two polymorphic forms and six solvates for N²,N⁶-bis(2-benzamidophenyl)pyridine-2,6-dicarboxamide (the pyridine variant). Three crystal structures of the benzene variant and seven structures of the pyridine variant were solved using single crystal X-ray diffraction. The crystal structures showed that the different modes of intramolecular hydrogen bonding strongly affect the conformation and folding of the molecules, which is most evidently seen with the strongly folded helical structure of the pyridine variant. NOESY experiments suggest that the intramolecular hydrogen bonding is stable enough to retain a folded or partially folded conformation even in solution. fi
dc.language.iso eng
dc.publisher RSC Publishing
dc.relation.ispartof CrystEngComm
dc.relation.uri http://pubs.rsc.org/en/content/articlelanding/2012/ce/c2ce25981h#!divAbstract
dc.rights © Royal Society of Chemistry. This is an author's final draft version of an article whose final and definitive form has been published by RSC.
dc.subject.other foldameeri
dc.subject.other oligoamidi
dc.subject.other kristallografia
dc.subject.other foldamer
dc.subject.other oligoamide
dc.subject.other crystallography
dc.title Structural analysis of two foldamer-type oligoamides the effect of hydrogen bonding on solvate formation, crystal structures and molecular conformation
dc.type Article en
dc.identifier.urn URN:NBN:fi:jyu-201211293120
dc.subject.kota 116
dc.contributor.laitos Kemian laitos fi
dc.contributor.laitos Department of Chemistry en
dc.contributor.oppiaine orgaaninen kemia fi
jyx.tutka.volyme 14
jyx.tutka.mnumber 21
jyx.tutka.pagetopage 7398-7407
dc.type.uri http://purl.org/eprint/type/SubmittedJournalArticle
dc.identifier.doi 10.1039/c2ce25981h
dc.date.updated 2012-11-29T10:39:43Z
dc.description.version Author's Final draft
eprint.status http://purl.org/eprint/type/status/PeerReviewed

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